Anti-Smad23 (6F7) Mouse Monoclonal Antibo

Anti-Smad2/3 (6F7) Mouse Monoclonal Antibody

Author: ApexBio

spu:

MA5156

shortsummary:

Anti-Smad2/3 (6F7) Mouse Monoclonal Antibody

51146-56-6 Biological Activity

M.Wt:

Calculated MW: 52 kDa; Observed MW: 52,60 kDa

Storage:

-20°C

DeliveryTime:

Ship with 3-5 days

caspofungin acetate price

ShippingType:

Blue ice

description:

Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the receptor-regulated Smads (R-Smads), which include Smad1, 2, 3, 5, and 8; the common-mediator Smad (co-Smad), Smad4; and the antagonistic or inhibitory Smads (I-Smads), Smad6 and 7 . Activated type I receptors associate with specific R-Smads and phosphorylate them on a conserved carboxy terminal SSXS motif. The phosphorylated R-Smad dissociates from the receptor and forms a heteromeric complex with the co-Smad (Smad4), allowing translocation of the complex to the nucleus. Once in the nucleus, Smads can target a variety of DNA binding proteins to regulate transcriptional responses .

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APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 23176 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.